A collaborative learning/teaching project about cannabis (marijuana) and the endogenous cannabinoid system, aka endocannabinoid system (ecs).
cannabisforhealth.ca (based in the Comox Valley, BC) is embarking on an ambitious undertaking - we intend to inform and educate all who are interested in health care about a brand new field of medicine, the endocannabinoid system (ecs).
Cannabis (marijuana) is a plant (weed) that produces chemical compounds in resin sacks (trichomes) which contain cannabinoids (thc, cbd, cbn, cbc…), terpenes, flavonoids, and terpenoids.
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Humans (and animals) produce endogenous cannabinoids (originating within the body) which attach to cannabinoid receptors throughout the body, and the reason cannabis works on so many different ailments is that plant cannabinoids (thc/cbd/cbn/cbg etc) attach to these same cannabinoid receptors.
The endocannabinoid system is responsible for homeostasis (balance, equilibrium, stability) and is the master system that regulates all bodily processes.
“The discovery of the endocannabinoid system is the single most important medical scientific discovery ever…” Dr. David Allen.
If you are interested in exploring this new discovery with us or want to contribute in some way, please email/pm/call ernie.
fmi firstname.lastname@example.org 250 338 3504
“The discovery of the endocannabinoid system is the single most important medical scientific discovery ever…” Dr. David Allen
DEFINITIONS FOR NEWBIES
To better understand Dr. David Allen’s video, we provide the following definitions of new (to some) words and phrases…
- cannabis (aka marijuana) is a plant (weed) indigenous to central Asia and the African subcontinent.
- cannabinoids (thc, cbd, cbn, cbg, etc) are the chemical compounds secreted by cannabis flowers.
- endogenous cannabinoid system (ecs), “named after the plant that led to its discovery, is perhaps the most important physiologic system involved in establishing and maintaining human health. Endocannabinoids and their receptors are found throughout the body: in the brain, organs, connective tissues, glands, and immune cells. In each tissue, the cannabinoid system performs different tasks, but the goal is always the same: homeostasis, the maintenance of a stable internal environment despite fluctuations in the external environment.” Dr. Martin Sulak
- entourage effect (whole plant medicine) “Take a close look at your cannabis buds. They’re covered in a sticky dusting of crystal resin, which contains hundreds of therapeutic compounds known as cannabinoids and terpenoids. We assume you’re well acquainted with THC and CBD, but these are just two among many important players working together to produce specific effects. This interactive synergy between marijuana compounds has been coined the “entourage effect,” and once you know what this is, you’ll see why medicines containing only THC or CBD aren’t sufficient for many medical conditions.” https://www.leafly.com/news/cannabis-101/cannabis-entourage-effect-why-thc–and-cbd-only-medicines-arent-g
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Transcript: The discovery of the endocannabinoid system
Dr. David Allen, retired cardiac surgeon
Published on Sep 25, 2014
Hello, my name is Dr. David Allen, I’m a retired cardiac surgeon and a member of the International Cannabinoid Research Society (ICRS). That means I’m a cannabinoid research scientist and I’m here to tell about the discovery of the endocannabinoid system (ECS), the significance and how it will change medicine.
We discovered the endocannabinoid system about 30 years ago. We really didn’t understand the significance of its discovery. We found out that this is a chemical communication that your body has. It’s not electrical, it’s chemical and it’s kind of like the hormone systems that people are familiar with. And your body makes these cannabinoids, endogenous, so they’re endocannabinoids and they perform some miraculous functions in the body and we’re just learning about the significance of these functions.
Basically, the endocannabinoid system is responsible for homeostasis. Most people don’t understand what that really means. It’s the body’s ability to maintain itself and function in the proper environment and so it’s critically important that doctors in the future understand this control mechanism.
We’re finding out that manipulation of the endocannabinoid system will control diabetes, it controls cancer, it controls whether you can survive a heart attack or stroke. So this is critically important for doctors to understand this new science.
The discovery of the endocannabinoid system is the single most important medical scientific discovery ever, and will save more lives than the discovery and application of sterile surgical techniques. I’m a heart surgeon saying that. More people will be saved by the manipulation of the endocannabinoid system than are currently saved by surgery.
We found out [from] studies that if you use cannabis for 20 years or more, just smoking cannabis, that it decreases the incidence of diabetes by 66%. There are studies that show when they specifically stress beta cells of the pancreas to try to kill them by oxidative techniques, that if you use cannabinoids, it protects the cells from oxidation. So really what this means is, you can use cannabis and decrease the incidence of diabetes by 66% or more if you use it other ways, if you eat it and you doctor currently can’t give you any medicine at all that decreases the incidence of diabetes by even 2%.
So this is a miracle that cannabis does this and it means that your use of cannabis will protect the beta cells of your pancreas from oxidation, That means basically all cannabis use is medical, regardless of whether you understand the science behind it or not.
Dr. Allen has written a detailed description of metabolism, homeostasis, and the endocannabinoid system in the current issue of Cannabis Digest (excerpt below), an excellent publication from the north wet coast of Canada.
David B. Allen M.D.
Homeostasis is a term that is used to describe both the survival of organisms in an ecosystem and the successful survival of cells inside of an organism. Organisms and cell populations can maintain homeostasis in an environment when they have a steady level of births and deaths. Metabolism of different foods or substrates (sugars, carbohydrates, starches, proteins and fats) requires a series of different protein enzymes that breaks down each of these food sources. Cells that have the necessary enzyme systems required to metabolize different types of food sources can adapt to scarcity of one food and extract energy from alternative food sources.